Chirality (from the Greek word “kheir”, meaning “hand”) is a fundamental concept that has been recognised in chemistry since the second half of nineteenth century. In fact, hard as they try, nobody could ever overestimate its importance, that extends from the synthesis of organic and inorganic compounds, pharmaceutical and biologically active molecules, theoretical studies and technological application, to understanding the basic principles and origin of the emergence of Life on our planet.
A chiral species is a single molecule or molecular assembly that cannot be superimposed with its mirror image. Chiral molecules are consequently present as two stereoisomers, called enantiomers, and, importantly, they are the main building blocks of living organism. On a daily basis, chiral molecules are conventionally used and produced by pharmaceutical, food, agrochemical, perfume, and cosmetics industries. As a result, chiral waste becomes an extremely important issue at present. Chiral compounds can be ecologically hazardous, due to their high biological activity, creating a global pollution problem. It is of note, that enantiomers have a different impact on living organisms making it extremely important to differentiate these stereoisomers, which is extremely a difficult and challenging task and usually requires highly specific and costly instruments. Yet, the stereoisomerism of contaminants is presently not considered in detail. For example, ~25% of all pesticides produced are chiral compounds and in many cases they are used as racemic mixtures, while about 70–80% of medical drugs are enantiopure molecules. In this context, the development of portable chemical sensors devices which are reliable, sensitive and rapid, capable of fast, simple and real-time in situ and on site analysis for sensing and discrimination of chiral molecules presents an attractive breakthrough target compared to existing standard instrumental methods.
Therefore, the aim of this Special Issue is to highlight and overview all aspects of chiral pollution on environment and corresponding detection by using modern analytical approaches.
This issue will also include the design and fabrication of organic/inorganic as well as hybrid sensitive materials. Different aspects will be covered ranging, for example, from the synthesis of the proper building blocks and their characterization to their eventual deposition in solid-state.
All types of papers, including comprehensive reviews on general environmental issues, mini reviews on specialized subjects, accounts of own research work, full experimental or theoretical papers, short communications, technical notes, comments, and others are welcome for consideration.
Prof. Dr. Victor Borovkov
Prof. Riina Aav
Prof. Roberto Paolesse
Dr. Manuela Stefanelli
Dr. Donato Monti
For more information visit Special Issue webpage